Our Review Summarypublished in the Annals of Oncology. Echoing the optimistic framing of a news release, this Newsweek story focused on the fact that some patients who took their drug saw their tumors shrink, including a quote calling the findings “very encouraging.” It also overlooked discussion of potential harms and and didn’t caution readers that tumor shrinkage doesn’t necessarily lead to longer survival. Why This MattersNearly half of women in the U.S. diagnosed with ovarian cancer don’t live more than five years. Targeted therapies like this one — which are designed to attack specific vulnerabilities in cancer cells — are being tested to treat cases that recur or resist standard treatment with surgery or chemotherapy. While targeted therapies are an important area of research, the public shouldn’t be oversold on early-phase trials or led to think that tumor shrinkage portends a cure. Criteria Not Satisfactory There’s … [Read more...] about Newsweek’s premature optimism about experimental ovarian cancer drug overlooks costs, harms and limitations of the evidence
Experimental lung cancer treatments
Jerome Check firmly believes that mifepristone, better known as the abortion pill, can extend and improve the lives of terminally ill lung cancer patients who have run out of treatment options. He has enough circumstantial evidence of this that the U.S. Food and Drug Administration gave him permission to formally test the drug in 40 advanced-stage patients. His clinical trial is the first step toward getting mifepristone approved as a palliative therapy. But Check has a problem. The 72-year old Melrose Park infertility specialist can’t get oncologists to send him patients. After 2½ years, he has enrolled only two of the 40 he needs. Both are doing very well on their daily mifepristone pill. Check’s problem doesn’t stem from skepticism about the potential benefits of the controversial drug, or his scientific credibility. The root of his trouble seems to be that he’s not an oncologist, and he has no “sponsor” – no deep-pocketed … [Read more...] about Can the abortion pill treat advanced lung cancer? This infertility expert wants to find out
Lindy Washburn NorthJersey Published 9:34 p.m. UTC Jun 25, 2018 MSK Bergen, the latest satellite center of one of the nation’s top-ranked cancer hospitals, is opening soon for outpatient care in Montvale, providing new treatment options for North Jersey patients who face the disease. Memorial Sloan Kettering Cancer Center, the Manhattan non-profit, has invested $185 million to renovate and equip a onetime corporate headquarters in northern Bergen County, about a mile from the Garden State Parkway. The new facility will bring treatment by Sloan's highly regarded specialists to more patients and expand opportunities for clinical trials of new drugs and procedures. With its famous name and marketing might, it will compete for new patients, as well as make outpatient care more convenient for the 10 percent of Sloan patients who currently travel from Bergen, … [Read more...] about More cancer treatment options for North Jersey patients as MSK Bergen opens in Montvale
Laurie McGinley, The Washington Post Published 8:21 am, Monday, June 4, 2018 Photo: Photo For The Washington Post By Scott McIntyre Image 1of/1 CaptionClose Image 1 of 1 Judy Perkins, right, paddles during a team canoe race in Wilton Manors, Fla. Perkins has undergone an experimental breast cancer treatment and has seen successful results. Judy Perkins, right, paddles during a team canoe race in Wilton Manors, Fla. Perkins has undergone an experimental breast cancer treatment and has seen successful results. Photo: Photo For The Washington Post By Scott McIntyre Researchers use immune-cell 'army' to battle another tough cancer 1 / 1 Back to Gallery A Florida woman diagnosed with advanced breast cancer, generally considered incurable, is free of the disease two-and-a-half years after a novel therapy used her … [Read more...] about Researchers use immune-cell ‘army’ to battle another tough cancer
Visit The Boston Globe Share on Twitter Share on Facebook Comment on this Scroll to top of page By Amy Sutherland May 16, 2018 DRAMBUIE THE GOLDEN RETRIEVER lies on his back on the floor, paws in the air, as his owner runs her hands over him. On this December night, like every night, Gina Alongi searches for sore spots and ticks, her fingers feeling for anything that might be amiss with her beloved dog. She starts with his chest and traces circles with her index and middle fingers down his torso. When she reaches the bare skin of his abdomen she pauses. She feels a small lump.It’s been eight years since Alongi flew to Ohio to buy a horse, only to come home with a new dog. Amid the thousands of quarter horses at this annual sale, one tent sold puppies. By the end of the day, there was a single one left. He looked so sad by himself. Alongi snuck him into her hotel room and then bought an additional plane ticket to fly him back to Westborough with her. Drambuie … [Read more...] about An experimental cancer treatment cured this dog. Could it work for people?