Drug companies and research organisations seeking a Covid-19 cure are turning to old molecules that are either out of production or those on which development work stopped due to lack of commercial viability. On Friday, India said it will join the global solidarity drug trial launched by the World Health Organisation (WHO), which means its patients will participate in trials for more than 20 or so molecules that may offer a way forward, reports DIVYA RAJAGOPAL in this week’s update on the state of Covid-19 vaccine and drug development. BCG VACCINE — Netherlands, Australia: Dutch and Australian scientists will study whether one of the oldest vaccines in use has the potential to suppress the SARS-CoV2 virus. The University of Melbourne has said it will recruit 4,000 healthcare workers to study whether the vaccine can become a preventive measure for frontline healthcare workers dealing with Covid-19 patients REMDESIVIR—US: A molecule developed by US drug maker … [Read more...] about Covid-19 race for cure: Drugs on trial
Advantages topical route of drug administration
Scientists at Baylor College of Medicine plan to recruit people who recovered easily from coronavirus and also those who ended up being hospitalized with it. The doctors would then see if there is a difference in their T-cells, a component of the immune system, and manufacture the components that seemed to aid in an easy recovery. … [Read more...] about Trump says this drug has ‘tremendous promise,’ but Fauci’s not spending money on it
WASHINGTON: Could a pair of decades-old, relatively inexpensive drugs be the solution to the novel coronavirus pandemic? Around the world, countries are expanding access to hydroxychloroquine (HCQ) and chloroquine (CQ), related compounds that are synthetic forms of quinine, which comes from cinchona trees and has been used for centuries to treat malaria. HQ which is the less toxic of the two, is also used as an anti-inflammatory to treat conditions like rheumatoid arthritis and lupus, purposes it is primarily known for outside the tropics. The medicines have shown early promise against the COVID-19 illness in early studies in France and China, which led US President Donald Trump this week to call them a "gift from God" - even as experts urge caution until bigger trials validate their effectiveness. Here is what you need to know. China used CQ on a trial of 134 patients in February, finding it was effective in reducing the severity of the illness, according to officials. But these … [Read more...] about What is chloroquine and can this decades-old drug cure the coronavirus?
NEW DELHI: Drug major Cipla on Thursday said it has received final approval from the US health regulator for generic Esomeprazole for oral suspension used for treatment of gastroesophageal reflux disease. The company has received final approval for its abbreviated new drug application (ANDA) for Esomeprazole for oral suspension in the strengths of 10mg, 20mg and 40mg from the United States Food and Drug Administration (USFDA), Cipla said in a statement. Cipla is the first company to file for the 10mg strength, it added. The product is a generic version of AstraZeneca Pharmaceutical's Nexium. It is indicated for the treatment of gastroesophageal reflux disease, risk reduction of NSAID-associated gastric ulcer, among others, Cipla said. According to IQVIA, Nexium and its generic equivalents had US sales of around USD 70 million for the 12 months ended November 2019, it added. Shares of Cipla were trading at Rs 389 per scrip on the BSE, up 3.27 per cent from the previous close. … [Read more...] about Cipla gets USFDA nod for generic acid reflux drug
“I am coming from an athletic environment and I will do everything to convince the athletes I am working with them and I am listening and I will do everything to create a fair environment for them.” he said. … [Read more...] about Coronavirus will not be opportunity for drug cheats says WADA chief
With no precedent, the International Olympic Committee (IOC) or World Anti-Doping Agency (WADA) may have to consider a structure like that used by Major League Baseball, where a player suspended during the season for a performance-enhancing drug violation is not be eligible for that year’s post-season. … [Read more...] about EXCLUSIVE-Olympics-Postponed 2020 Games raises questions about drug cheats-USADA